What is a common reaction for individuals allergic to Penicillin?

A skin rash is a common reaction for individuals allergic to Penicillin. This allergic reaction typically manifests as hives, rashes, or other dermatological symptoms, which are signs that the immune system is responding to the presence of the antibiotic. The immune system mistakenly identifies Penicillin as a harmful substance, triggering the release of histamines and other chemicals that cause inflammation and skin irritations.

While fever, breathlessness, and headache can be associated with various medical conditions or medications, they are not the hallmark symptoms of a Penicillin allergy. Fever can occur due to various infections or reactions but is not specific to drug allergies. Breathlessness may be indicative of a more severe allergic response, such as anaphylaxis, but is much less common than a rash alone. Headaches can arise from many causes unrelated to allergies, making them less relevant in this context.